Name: Cajun Chicken Rotini in Creamy Mozzarella Velveeta Sauce
Prep time: 15 min
Cook time: 25 min
Total time: 40 min
Cuisine: Cajun
Ingredients: 12 oz rotini pasta; 1 lb boneless skinless chicken breasts; 2 tbsp Cajun seasoning; 1 tbsp olive oil; 2 tbsp butter; 3 cloves garlic, minced; 1 cup chicken broth; 1 cup heavy cream; 8 oz Velveeta, cubed; 1 cup shredded mozzarella; 1/2 tsp fine salt (to taste); 1/4 tsp black pepper; 2 tbsp chopped fresh parsley (optional, for garnish)

If you’re craving a dish that’s equal parts bold, creamy, and comforting, Cajun Chicken Rotini in Creamy Mozzarella Velveeta Sauce is about to become your new favorite dinner. This recipe marries tender, spice-rubbed chicken with perfectly cooked rotini, all blanketed in a velvety sauce that’s rich with mozzarella and Velveeta cheese. The Cajun seasoning gives it a smoky, slightly spicy kick that makes every bite an irresistible mix of comfort and excitement.

Imagine a cozy dinner table, a steaming plate in front of you, the sauce clinging to each spiral of pasta, and that creamy-cheesy aroma wafting through the air. This is the kind of meal that satisfies weeknight hunger yet feels special enough to serve when you have guests over. It’s the culinary equivalent of a warm hug—with a little Cajun attitude.

Why You’ll Love This Cajun Chicken Rotini in Creamy Mozzarella Velveeta Sauce

This recipe strikes the perfect balance between easy and impressive. The Cajun spices elevate the flavor without overpowering it, while the mozzarella and Velveeta make the sauce irresistibly smooth and cheesy. It’s a one-pan wonder in spirit—simple steps, big flavors, and easy cleanup. Whether you’re a seasoned cook or just finding your kitchen confidence, this dish delivers a crowd-pleasing dinner with minimal fuss.

Ingredients for Cajun Chicken Rotini in Creamy Mozzarella Velveeta Sauce

Each ingredient plays a role in building layers of flavor and creating that creamy, comforting texture.

Rotini Pasta – Its spiral shape perfectly holds the cheesy sauce in every bite.
Boneless Skinless Chicken Breasts – Lean, tender, and perfect for soaking up Cajun spices.
Cajun Seasoning – Adds that smoky, mildly spicy, Louisiana-style flavor.
Olive Oil – Helps sear the chicken for a golden crust while keeping it juicy.
Velveeta Cheese – Melts into a silky, smooth sauce that coats the pasta beautifully.
Mozzarella Cheese – Adds stretchy, melty goodness and mild creaminess.
Heavy Cream – The key to a rich, indulgent sauce.
Garlic – Brings warmth and depth to the sauce.
Chicken Broth – Helps create the sauce base while infusing savory flavor.
Butter – Adds richness and a glossy finish.
Salt & Pepper – Balances and enhances all the flavors.

How To Make the Cajun Chicken Rotini in Creamy Mozzarella Velveeta Sauce

Step 1: Season and Sear the Chicken

Pat the chicken breasts dry, then rub them generously with Cajun seasoning, salt, and pepper. Heat olive oil in a large skillet over medium-high heat and sear the chicken for 4–5 minutes per side until golden brown and cooked through. Remove from skillet and let rest.

Step 2: Cook the Pasta

Bring a pot of salted water to a boil. Cook rotini pasta according to package directions until al dente. Drain and set aside, reserving 1/2 cup of pasta water.

Step 3: Make the Sauce Base

In the same skillet used for chicken, melt butter over medium heat. Add minced garlic and sauté for 30 seconds until fragrant. Pour in chicken broth and heavy cream, stirring to combine.

Step 4: Add the Cheeses

Reduce heat to low and stir in Velveeta until fully melted. Add mozzarella, stirring until the sauce is smooth and creamy.

Step 5: Combine Everything

Slice the cooked chicken into strips. Add pasta to the sauce, tossing gently to coat. Stir in the chicken and adjust consistency with reserved pasta water if needed.

Step 6: Serve

Plate immediately, garnishing with fresh parsley or extra Cajun seasoning for a colorful finish.

Serving and Storing Cajun Chicken Rotini in Creamy Mozzarella Velveeta Sauce

This recipe comfortably feeds 4 people and makes for a satisfying main course. Serve it hot straight from the skillet so the sauce is at its creamiest and the pasta perfectly coated. For leftovers, store in an airtight container in the refrigerator for up to 3 days. When reheating, add a splash of milk or chicken broth to restore the sauce’s creamy texture.

If you’d like to freeze it, store portions in freezer-safe containers for up to 2 months. Thaw in the fridge overnight before gently reheating on the stovetop.

What to Serve With Cajun Chicken Rotini in Creamy Mozzarella Velveeta Sauce

1. Garlic Bread

Perfect for soaking up every drop of that cheesy Cajun sauce.

2. Steamed Broccoli

A fresh, healthy side that balances the richness of the pasta.

3. Side Salad with Ranch Dressing

The crisp greens and creamy dressing complement the bold Cajun flavors.

4. Roasted Asparagus

Earthy and slightly charred, asparagus pairs beautifully with the creamy sauce.

5. Cornbread

Adds a touch of sweetness and Southern charm to your meal.

6. Sautéed Green Beans

Lightly seasoned green beans provide a fresh, crisp contrast.

7. Cajun-Spiced Roasted Potatoes

Double up on the Cajun flavor with crispy, seasoned potatoes.

8. Grilled Corn on the Cob

Sweet corn brings out the smoky notes in the seasoning.

Frequently Asked Questions

Q1: Can I use a different type of pasta?
Yes! Penne, fusilli, or bow-tie pasta will all work well. Just adjust the cooking time according to the package directions.

Q2: Is there a substitute for Velveeta cheese?
If you prefer not to use Velveeta, you can use extra mozzarella and add a bit of cream cheese for creaminess.

Q3: Can I make this recipe less spicy?
Absolutely. Reduce the Cajun seasoning or choose a mild version to tone down the heat.

Q4: How can I make it even more flavorful?
Add sautéed onions and bell peppers to the sauce for extra depth and color.

Q5: Can I make it ahead of time?
You can cook the chicken and pasta ahead, then prepare the sauce and combine just before serving for the best texture.

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And let me know in the comments how yours turned out. Did you add vegetables or keep it classic? Did you use extra cheese on top?
I love hearing how others make these recipes their own. Questions are welcome too—let’s help each other cook smarter.

Conclusion

Cajun Chicken Rotini in Creamy Mozzarella Velveeta Sauce is comfort food with a flavorful twist. The smoky Cajun seasoning, tender chicken, and ultra-creamy sauce make it a satisfying meal any night of the week. It’s quick enough for busy evenings yet indulgent enough for special occasions. One bite, and you’ll see why it deserves a spot in your recipe rotation.